| Name |
North or east end |
South or west end |
U.S. Highways (approximate, based on 1926 plan and later additions) |
Notes |
| Albert Pike Highway |
Hot Springs, Arkansas |
Colorado Springs, Colorado |
US 270, US 64, US 183, US 154, US 50, US 85 |
| Arrowhead Trail |
Salt Lake City, Utah |
Los Angeles, California |
US 91 |
| Atlantic Highway |
Calais, Maine |
Miami, Florida |
US 1, US 25, US 17, US 1 |
| Atlantic-Pacific Highway |
New York, New York |
Los Angeles, California |
US 1, US 211, US 15, US 33, US 60, US 52, US 460, US 50, US 54, US 70, US 60 |
| Atlantic Yellowstone Pacific Highway |
Chicago, Illinois |
Sioux Falls, South Dakota |
US 20, US 218, US 18 |
| Baltimore Pike |
Baltimore, Maryland |
Philadelphia, Pennsylvania |
|
| Bankhead Highway |
Washington, D.C. |
San Diego, California |
US 1, US 15, US 70, US 170, US 29, US 78, US 70, US 67, US 80 |
| Bee Line Highway |
Chicago, Illinois |
New Orleans, Louisiana |
|
| Ben Hur Highway |
St. Louis, Missouri |
Fort Dodge, Iowa |
|
| Black and Yellow Trail |
Chicago, Illinois |
Yellowstone National Park |
US 41, US 16, US 14, US 16, US 20 |
| Blackhawk Highway |
Dixon, Illinois |
Beloit, Wisconsin |
IL 2, IL 251, US 51 |
| California-Banff Bee Line |
|
|
|
| Cannon Ball Route |
Chicago, Illinois |
Hannibal, Missouri |
|
| Capital Route |
Omaha, Nebraska |
Austin, Texas |
|
| Chicago, Kansas City and Gulf Highway |
Chicago, Illinois |
Galveston, Texas |
|
| Colorado to Gulf Highway |
Denver, Colorado |
Galveston, Texas and Brownsville, Texas |
US 85, US 385, US 370, US 81, US 181 |
| Columbia River Highway |
Pendleton, Oregon |
Portland, Oregon |
US 30 |
| Cooley Highway |
Grand Rapids, Minnesota |
Sisseton, South Dakota |
|
| Cornhusker Highway |
Sioux City, Iowa |
Oklahoma City, Oklahoma |
|
| Custer Battlefield Highway |
Omaha, Nebraska |
Glacier National Park |
US 75, US 16, US 116, US 87E, US 87 |
| Dallas-Canadian-Denver Highway |
Boulder, Colorado |
Galveston, Texas |
US 85, US 50, US 83, US 70, US 77 |
| Daniel Webster Highway |
|
|
|
| Detroit-Lincoln-Denver Highway |
Detroit, Michigan |
Denver, Colorado |
US 12, US 32, US 38 |
| Dixie Highway |
Chicago, Illinois and Sault Ste. Marie, Michigan |
Miami, Florida |
Illinois 1, US 136, US 31, Indiana 37, US 150, US 31W |
| Dixie Bee Line |
Chicago, Illinois |
Nashville, Tennessee |
US 41, US 241 |
| Dixie Overland Highway |
Savannah, Georgia |
San Diego, California |
US 80, US 84, US 380, US 366, US 80 |
| Evergreen National Highway |
Victoria, British Columbia |
El Paso, Texas |
US 99, US 10, US 97, US 410, US 95, US 30, US 30N, US 91, US 95, US 66 |
| Egyptian Trail |
Chicago, Illinois |
Cairo, Illinois |
|
| Florida Short Route |
|
|
|
| George Washington National Highway |
Savannah, Georgia |
Seattle, Washington |
|
| Geysers-to-Glaciers Highway |
Glacier National Park |
Yellowstone National Park |
US 89 W from West Yellowstone to Shelby, Montana; US 2 from Shelby to Cut Bank, Montana; and MT 213 from Cut Bank to the Canada–US border[1] |
| Glacier to Gulf Motorway |
Calgary, Alberta |
Tampico, Mexico |
|
| Glacier Trail |
Seattle, Washington |
Jacksonville, Florida |
|
| Grant Highway |
Chicago, Illinois |
Portland, Oregon |
US 20 |
| Great White Way |
Davenport, Iowa |
Council Bluffs, Iowa |
|
| International Peace Highway |
Quebec, Quebec and Rouses Point, New York |
Laredo, Texas and Mexico City, Mexico |
|
| Jackson Highway |
Chicago, Illinois |
New Orleans, Louisiana |
US 152, US 52, US 31, US 168, US 68, US 31, US 43, US 45, US 11 |
| Jefferson Highway |
Winnipeg, Manitoba |
New Orleans, Louisiana |
US 59, US 2, US 71, US 10N, US 10, US 65, US 69, US 71/US 73E, US 73, US 75, US 69, US 67, US 271, US 80, US 171, US 71, US 61 |
| Jefferson Davis National Highway |
Washington, D.C. |
San Diego, California |
US 1, US 278, US 29, US 80, US 43, US 90, US 96, US 277, US 90 |
| King of Trails |
Winnipeg, Manitoba |
Galveston, Texas and Brownsville, Texas |
US 75/US 81, US 75/US 77, US 75, US 73, US 73E, US 50, US 73W, US 75, US 77, US 81, US 181, US 96 |
| Lackawanna Trail |
Binghamton, New York |
Delaware, New Jersey |
US 11,[2] US 611[3] |
| Lakes to Gulf Highway |
Duluth, Minnesota |
Galveston, Texas |
|
| Lakes-to-Sea Highway |
Atlantic City, New Jersey |
Erie, Pennsylvania |
US 30, US 120, US 22, US 322, US 19 |
| Lee Highway |
New York, New York |
San Francisco, California |
US 1, US 211, US 11, US 72, US 70, US 366, US 80, US 180, US 80, US 101 |
| Lewis and Clark Highway |
Missoula, Montana |
Lewiston, Idaho |
|
| Liberty Highway |
New York, New York |
Cleveland, Ohio |
New Jersey 4, New Jersey 17, New York 17, New York 430, New York 394, US 20[4] |
| Lincoln Highway |
New York, New York |
San Francisco, California |
US 1, US 30, US 40, US 93, US 50, US 99, US 48 |
| Logan-Lee Highway |
Rock Island, Illinois |
Paducah, Kentucky |
US 67, Illinois 3 |
| Lone Star Route |
Chicago, Illinois |
Lake Charles, Louisiana (earlier Brownsville, Texas) |
US 66, US 67, US 63, US 165 |
| Lone Star Trail |
St. Augustine, Florida |
Los Angeles, California |
US 1, US 90, US 84, US 67, US 290, US 80 |
| Magnolia Route |
|
|
|
| Meridian Highway |
Winnipeg, Manitoba |
Mexico City, Mexico |
US 81 |
| Mississippi River Scenic Highway |
Winnipeg, Manitoba and Port Arthur, Ontario |
Fort Myers, Florida and Port Arthur, Texas |
US 75, US 2, US 71, US 10N, US 10, US 61, US 55, US 61, US 90; US 49E, US 49, US 98, US 90, US 19, US 41 |
| Mississippi Valley Highway |
Ely, Minnesota |
Gulfport, Mississippi (earlier New Orleans, Louisiana) |
US 53, US 61, US 55, US 161, US 67, US 51, US 45, US 11, US 49 |
Earlier known as the Burlington Way |
| National Old Trails Road |
Washington, D.C. and Baltimore, Maryland |
Los Angeles, California |
US 240/US 40, US 40, US 50N, US 50, US 350, US 85, US 70, US 66 |
| National Park-to-Park Highway |
Loop connecting National Parks |
|
US 99, US 48, US 40, US 99E, US 99, US 10, US 195, US 95, US 2, US 87, US 87W, US 20, US 185, US 85, US 50, US 285, US 450, US 550, US 64, US 666, US 66 |
| National Parks Highway |
Boston, Massachusetts and New York, New York |
Seattle, Washington |
|
Also known as the Northwest Trail |
| National Roosevelt Midland Trail |
Washington, D.C. and Newport News, Virginia (earlier Oyster Bay, New York) |
Los Angeles, California |
US 60, US 150, US 50, US 40, US 40N, US 40, US 40S, US 50, US 6 |
| National White Way |
|
|
|
| New Santa Fe Trail |
Kansas City, Mo. |
Los Angeles |
US 50, US 350, US 85, US 66 |
| Old Oregon Trail |
Independence, Missouri |
Seaside, Oregon and Olympia, Washington |
US 40, US 30, US 26, US 20, US 87E, US 30N, US 30 |
| Old Spanish Trail |
St. Augustine, Florida |
San Diego, California |
US 1, US 90, US 80 |
| Ozark Trails |
Kansas City, Missouri, Hannibal, Missouri, St. Louis, Missouri, and Memphis, Tennessee |
Denver, Colorado, Las Vegas, New Mexico, and El Paso, Texas |
|
| Pacific Highway |
Vancouver, British Columbia |
San Diego, California |
US 99, US 40, US 101 |
| Pershing Way |
Winnipeg, Manitoba |
New Orleans, Louisiana |
|
| Pikes Peak Ocean to Ocean Highway |
New York, New York |
Los Angeles, California (earlier San Francisco, California) |
US 22, US 250, US 36, US 136, US 36, US 40N, US 40S, US 50, US 91 |
Also known as the Pershing Transport Route |
| Puget Sound-to-Gulf Highway |
|
|
|
| Red Ball Route |
|
|
|
| River-to-River Road |
Davenport, Iowa |
Council Bluffs, Iowa |
|
| Southern National Highway |
|
|
|
| Southwest Trail |
Chicago, Illinois |
El Paso, Texas |
US 32, US 65, US 50S, US 81, US 160, US 281, US 60, US 366 |
| Susquehanna Trail |
Buffalo, New York |
Washington, D.C. |
US 20, US 15, US 111/US 240 |
| Theodore Roosevelt International Highway |
Portland, Maine |
Portland, Oregon |
US 302, US 2, US 11, US 104, US 23, US 2, US 95, US 195, US 295, US 410, US 30 |
| Three C Highway |
Cleveland, Ohio |
Cincinnati, Ohio |
US 42 |
| Transprovincial Highway |
Ottawa |
Toronto |
|
Later Ontario Highway 2 and Ontario Highway 15 |
| Victory Highway |
New York, New York |
San Francisco, California |
US 1, US 40, US 40S, US 83, US 40N, US 40 |
| White River Trail |
Springfield, Missouri |
Ponca City, Oklahoma |
|
| White-way 7 Highway |
Chicago, Illinois |
Omaha, Nebraska |
US 32 |
In Iowa, created from segments of the River to River Road from Davenport to Redfield, and the Great White Way from Dexter to Council Bluffs. |
| William Penn Highway |
New York, New York |
Pittsburgh, Pennsylvania |
US 22 |
| Yellowstone Highway |
Denver, Colorado |
Yellowstone National Park |
|
| Yellowstone Trail |
Plymouth, Massachusetts |
Seattle, Washington |
US 20, US 30, US 41, US 110, US 10, US 212, US 12, US 10, US 195, US 295, US 410, US 97, US 10 |